开源中国 开源世界2019_开源人工胰腺病将在2019年成为糖尿病的新护理标准
开源中国 开源世界2019
I've been a Type 1 diabetic for over 25 years. Diabetes sucks. They actually give you an award for staying alive for years on insulin. Diabetics don't usually die of old age, they die of heart disease or stroke, kidney failure, and while they're at it they may go blind, get nerve damage, amputation, and a bunch of other stuff. It used to be a death sentence but when insulin was introduced as a treatment in 1921, there was a chance for something new.
我已经成为25岁以上的1型糖尿病患者。 糖尿病很烂。 实际上，他们因在胰岛素上存活数年而获得奖励。 糖尿病患者通常不会死于老年，而是死于心脏病或中风，肾脏衰竭，而在这种情况下，他们可能会失明，受到神经损伤，截肢和其他一些疾病。 它曾经是一个死刑判决，但是在1921年采用胰岛素作为治疗方法时，就有了一些新的机会。
The idea is if you keep your blood sugars close to normal - if you can simulate your non-working pancreas - you'll get hit by an ice cream truck! At least, that's how I hope I go. :)
这个想法是，如果您的血糖保持在正常水平-如果您可以模拟不工作的胰腺-您会被冰淇淋车撞到！ 至少，这就是我希望我去的方式。 :)
- Early on it was boiling big gauge steel needles and pork insulin to dose, and peeing on a stick to get a sense of sugar levels. 最初，它是用大规格的钢针和猪肉胰岛素煮沸至一定剂量，然后撒在棍子上撒尿以获得糖水平的感觉。
- Then it was a dozen finger pricks a day and a half dozens manual shots with a syringe. 然后每天要打十二根手指，并用注射器进行六十次手动射击。
- Then it was inserted continuous glucose meters and insulin pumps that - while not automatic - mean less invasive treatment and greater control. 然后将其插入连续的血糖仪和胰岛素泵中，尽管不是自动的，但意味着侵入性治疗更少，控制更强。
Today, we are closing the loop. What's the loop? It's this:
今天，我们正在结束循环。 什么循环？ 是这样的：
- Consider my glucose levels, what I'm about to eat, and what I'm about to to (and dozens of other environmental factors) 考虑我的血糖水平，我要吃的东西以及我要吃的东西(以及许多其他环境因素)
- Dose myself with insulin 给自己服用胰岛素
- GOTO 1. Every few hours, or every few minutes, depending on the situation.转到1.根据情况，每隔几个小时或每几分钟。
I do that. Manually. Every diabetic does, and the mental pressure - the intense background psychic weight of it all - is overwhelming. We want to lower the cognitive load of diabetes. This is a disease where you may not live as long if you're not good at math. Literally. That's unfair.
我做到了手动。 每一位糖尿病患者都这样做，而且精神压力-包括所有背景因素在内的强烈心理压力-势不可挡。 我们想降低糖尿病的认知负担。 如果您不擅长数学，那么您可能无法长寿。 从字面上看。 这不公平。
The community is "looping" by allowing an algorithm to make some of those decisions for me.
通过允许算法为我做出一些决策，社区正在“循环”。
I've personally been looping with an open source artificial pancreas for over two years. It's night and day from where I started with finger sticks and a half dozen needle sticks a day. It's not perfect, it's not automatic, but Open Source Pancreas are "Tesla autopilot for diabetes." It doesn't always park the car right or stop at every stop light, but it works very hard to keep me in-between the lines and going straight ahead and now that I have it, I can't imagine living without it.
我个人使用开放源人造胰腺已有两年多了。 从那天开始的黑夜开始，我每天都用手指棒和六根针棒。 它不是完美的，不是自动的，但是开源胰腺是“特斯拉糖尿病自动驾驶仪”。 它并不总是将汽车停在正确的位置或在每个停车灯处停下，但它很难使我保持在直线之间并一直向前行驶，而现在有了它，我无法想象没有它。
I sleep through the night while my Loop makes tiny adjustments every five minutes to keep my sugars as flat as possible. I don't know about you but my pancreas sits on my nightstand.
我整夜不眠，而Loop则每隔五分钟进行一些微调，以使糖分尽可能平整。 我不认识你，但我的胰腺坐在我的床头柜上。
它正在发生并且无法停止 (It's happening and it can't be stopped)
Seven years ago I wrote about The Sad State of Diabetes Technology in 2012. Three years ago The Promising State of Diabetes Technology in 2016 and last year The Extremely Promising State of Diabetes Technology in 2018. There's a great comment from the first blog post in 2012 where Howard Loop shared his frustration with the state of things. Unlike most commenters on the Internet, amazingly Howard took action and started the Tidepool Organization! Everything in his comment from 7 years ago is happening.
七年前，我写了2012年的《糖尿病技术的悲伤状态》 。 三年前，《 2016年糖尿病技术的发展前景》和去年《 2018年糖尿病技术的发展前景》 。 2012年第一篇博客文章中有一个很好的评论，霍华德·洛普(Howard Loop)分享了他对事物状态的沮丧。 与Internet上大多数评论员不同，霍华德惊奇地采取了行动，成立了Tidepool Organization ！ 他7年前的评论中的所有事情都在发生。
It's 2019 and things are really looking up. The open source DIY diabetes community is thriving. There are SEVERAL open pancreas systems to choose from and there's constant innovation happening with OpenAPS and Loop/LoopKit.
现在是2019年，情况真的在好转。 开源DIY糖尿病社区正在蓬勃发展。 有数种开放式胰腺系统可供选择， OpenAPS和Loop / LoopKit不断创新。
- OpenAPS runs on devices like Raspberry Pi Zeros and is a self-contained pancreas with the communications and brain/algorithm all on the main device. OpenAPS在Raspberry Pi Zeros之类的设备上运行，并且是一个独立的胰腺，所有主要设备上均具有通信和大脑/算法。
- Loop runs on an iPhone and uses a "RileyLink" devices that bridges the RF (Radio Frequency) insulin pump communications with modern Bluetooth. Loop在iPhone上运行，并使用“ RileyLink”设备将RF(射频)胰岛素泵通信与现代蓝牙桥接起来。
The first bad part is I am running a 15 year old out of warranty cracked insulin pump I bought on Craigslist. Most new pumps are locked down, and my old pump is the last version that supported remote control. However, the Loop open source project announced support for a second pump this week, the OmniPod Eros. This is the first time an "in warranty" pump has been supported and it also proves the larger point made by the diabetes community. We Are Not Waiting. We want open choice and open data and open choices that put us in control.
第一个坏处是我正在使用我在Craigslist上购买的15年保修保修破裂的胰岛素泵。 大多数新泵都被锁定，而我的旧泵是支持远程控制的最新版本。 但是，Loop开源项目宣布本周将支持第二个泵OmniPod Eros。 这是首次支持“保修期内”的泵，这也证明了糖尿病社区的更大观点。 我们不等。 我们想要开放的选择，开放的数据和开放的选择，使我们能够掌控一切。
Read about the history of Loop by original developer Nate Racklyeft. As he points out, a thing like Loop or OpenAPS is the result of a thousand little steps and innovation by countless community members who are so generous with their time.
阅读有关原始开发人员Nate Racklyeft的Loop的历史。 正如他指出的那样，Loop或OpenAPS之类的东西是无数的社区成员一千个小步骤和创新的结果，他们对时间如此慷慨。
The first system to run it was a Raspberry Pi; the code was a series of plugins, written with the help of Chris Hannemann, to the openaps toolkit developed by Ben West in collaboration with Dana Lewis and Scott Leibrand. I’m still in awe of the elegant premise in Ben’s design: a system of repeatable, recordable, and extendable transform commands, all backed by Git. The central plugin of the toolkit is decocare: Ben’s 5-year magnum opus, a reverse-engineered protocol of the Minimed Carelink USB radio to command insulin pumps.
运行它的第一个系统是Raspberry Pi。 代码是一系列的插件，用的帮助书面克里斯Hannemann的，到openaps工具包所开发奔西中合作与达纳·刘易斯和斯科特Leibrand 。 我仍然对Ben设计中的优雅前提感到敬畏：可重复，可记录和可扩展的转换命令系统，均由Git支持。 该工具包的核心插件是decocare ：Ben的5年大瓶装作品，是Minimed Carelink USB无线电的反向工程协议，用于命令胰岛素泵。
There's an amazing write up by Pete Schwamb, one of the core members of the community who works on Loop full time now, on how Software Defined Radios have allowed the community to "sniff" the communication protocols of insulin pumps in the RF spectrum and reverse engineer the communications for the Medtronic and now Omnipod Eros Insulin Pumps. It's a fascinating read that really illustrates how you just need the right people and a good cause and you can do anything.
社区的核心成员之一，现在全职从事Loop的Pete Schwamb撰写了一篇惊人的文章，内容涉及软件定义的无线电如何使社区“嗅探”胰岛素泵在RF频谱中的通信协议并反向为Medtronic和现在的Omnipod Eros胰岛素泵设计通讯。 这是一本引人入胜的读物，真正说明了您如何需要合适的人选和良好的事业，并且您可以做任何事情。
You can watch my video presentation "Solving Diabetes with an Open Source Artificial Pancreas" where I offer an overview of the problem, a number solutions offered over the year, and two open source pancreas options in the form of LoopKit and OpenAPS.
您可以观看我的视频演示“使用开源人工胰腺解决糖尿病”，其中概述了该问题，一年中提供了多种解决方案以及两个以LoopKit和OpenAPS形式出现的开源胰腺选项。
The community members and organizations like Tidepool and the Nightscout Foundation are working with the FDA to take projects and concepts like an open source pancreas system from a threat based on years of frustration to a bright future based on mutual collaboration!
潮汐池( Tidepool)和Nightscout基金会等社区成员和组织正在与FDA合作，以实施诸如开源胰腺系统之类的项目和概念，从基于多年挫折的威胁到基于相互合作的美好未来！
In March, 2018, the FDA announced a de novo iCGM (integrated CGM) designation. A de novo designation is the FDA process for creating new device classifications, in this case moving qualifying CGMs from Class-III, the highest FDA risk classification, to Class-II with Special Controls. The first CGM to get this designation is the Dexcom G6.
2018年3月， FDA宣布了从头iCGM (集成CGM)的称号。 从头命名是FDA创建新设备分类的过程，在这种情况下，将合格的CGM从FDA风险最高的III类转移到具有特殊控制的II类。 第一个获得此称号的CGM是Dexcom G6。
Imagine a future where someone could buy a supported and in-warranty "iPump," download an officially supported app or package, and start looping! We could have world of open and interoperable devices and swappable algorithms.
想象未来，有人可以购买受支持且保修期内的“ iPump”，下载受官方支持的应用或程序包，然后开始循环播放！ 我们可能拥有开放和可互操作的设备以及可交换算法的世界。
In October of 2018 the non-profit Tidepool organization announced its intent to deliver the Loop app as a supported and FDA-regulated mobile app in the Apple App Store! This is happening, people but we are just getting started.
在2018年10月，非营利性Tidepool组织宣布了其打算在Apple App Store中提供Loop应用程序作为受支持且受FDA监管的移动应用程序的意图！ 发生这种情况的人，但是我们才刚刚开始。
To learn more, start reading.
要了解更多信息，请开始阅读。
-
Loop - https://loopkit.github.io/loopdocs/
循环-https: //loopkit.github.io/loopdocs/
-
OpenAPS - https://openaps.org/
OpenAPS- https: //openaps.org/
-
Tidepool - https://www.tidepool.org/
Tidepool - https://www.tidepool.org/
Also, if you're diabetic, consider buying a Nightscout Xbox Avatar accessory so you can see yourself represented while you game!
另外，如果您患有糖尿病，可以考虑购买Nightscout Xbox Avatar配件，以便在游戏时能看到自己的身影！
Sponsor: Suffering from a lack of clarity around software bugs? Give your customers the experience they deserve and expect with error monitoring from Raygun.com. Installs in minutes, try it today!
发起人：是否对软件错误缺乏明确的了解？ 通过Raygun.com进行错误监视，为您的客户提供应有的期望和期望的体验。 几分钟即可安装，立即尝试！
关于斯科特 (About Scott)
Scott Hanselman is a former professor, former Chief Architect in finance, now speaker, consultant, father, diabetic, and Microsoft employee. He is a failed stand-up comic, a cornrower, and a book author.
斯科特·汉塞尔曼(Scott Hanselman)是前教授，前金融首席架构师，现在是演讲者，顾问，父亲，糖尿病患者和Microsoft员工。 他是一位失败的单口相声漫画家，一个玉米种植者和一本书的作者。
开源中国 开源世界2019